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Crocker ’12 to Clerk for Justice Scalia

By University of Virginia School of Law - Brian McNeill | Published May 17, 2012
One University of Virginia School of Law student walking down the Lawn on Sunday has lined up the most prestigious job a law graduate can have. Graduating law student Katherine Mims Crocker will clerk for U.S. Supreme Court Justice Antonin Scalia during the 2013-14 term.
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Vivid details

By Harvard Gazette | Published May 17, 2012

A landmark effort to sequence the genome of a South American butterfly has revealed the key behind its ability to mimic other butterflies.

A first for science, the genome sequencing work is the product of an international group of researchers, dubbed the Heliconius Genome Consortium, who examined the genome of the Postman butterfly (Heliconius melpomene), a well-known species that lives in the Peruvian Amazon. Using that data as a guide, they then examined the genetic makeup of two other closely related butterfly species – Heliconius timareta and Heliconius elevatus.

The three species were selected for the study because they share similar color patterns on their wings as a way to ward off predators.

The consortium’s surprising finding, as described in a paper published May 16 in Nature, is that the species look similar because they share the parts of their DNA that deal with color patterns.

“Heliconius butterflies exhibit an extraordinary amount of color-pattern mimicry between the species, and with species in other groups,” said Jim Mallet, distinguished lecturer on organismic and evolutionary biology and associate of the Department of Organismic and Evolutionary Biology. “We have found that species share the parts of the genome that code for color pattern loci, with a major impact on the survival of these butterflies in the wild.”

The genetic sharing among species, researchers believe, is the result of hybridization. Considered extremely rare, particularly in animals, hybridization occurs when two different species interbreed in the wild.

The resulting hybrid offspring share traits with both mother and father. Though often considered evolutionary dead-ends, hybrids occasionally interbreed with a parent species, in the process introducing new genes that can help populations adapt to new or changing environments.

“What we show is that one butterfly species can gain its protective color pattern genes ready-made from a different species by hybridizing [or interbreeding] with it — a much faster process than having to evolve one’s color patterns from scratch,” said Kanchon Dasmahapatra, a postdoctoral researcher at the University College London’s Department of Genetics, Evolution and Environment, and a co-author of the paper.

“This project really changes how we think about adaptation in general,” said Marcus Kronforst, a Bauer Fellow at Harvard, who participated in the sequencing. “Evolutionary biologists often wonder whether different species use the same genes to generate similar traits, like the mimetic wing patterns of Heliconius butterflies. This study shows us that sometimes different species not only use the same genes, but the exact same stretches of DNA, which they pass around by hybridization.”

A total of 80 researchers in 32 research universities and institutions from eight countries worked on the genome project, while a subset of nine laboratories funded the sequencing of the 290 million DNA bases using high-throughput technologies, allowing the work to proceed without major dedicated grant funding.

Sequencing work for the consortium was carried out at the Baylor College of Medicine, which performed the main reference sequence, and at the University of Edinburgh, GenePool, where the resequencing was performed.

Posted in Butterfly, Department of Organismic and Evolutionary Biology, Faculty of Arts and Sciences, FAS, Genome, genome sequencing, HarvardScience, Heliconius elevatus, Heliconius Genome Consortium, Heliconius melpomene, Heliconius timareta, Hybrid, Hybridization, James Mallet, Life Sciences, Peter Reuell | Tagged , , , , , , , , , , , , , , , | Comments Off

A maestro and a wordsmith

By Harvard Gazette | Published May 17, 2012

This is one in a series of profiles showcasing some of Harvard’s stellar graduates.

It’s often been said that the Harvard undergraduate experience is what one makes of it. Senior Matt Aucoin took that message to heart. He leaves campus having immersed himself in Harvard’s rich worlds of poetry and music, with a degree in English, a passion for writing and composing, and a future destined for The New Yorker, or the conductor’s podium, or both.

A resident of Kirkland House, Aucoin was poetry editor of the literary journal The Harvard Advocate. His thesis, a collection of poetry titled “Aftermusic,” recently won a Thomas T. Hoopes Prize for outstanding scholarly work or research. In 2009, he received several coaching sessions with classical music legend James Levine, and he used a 2010 Artist Development Fellowship from Harvard’s Office for the Arts to study at the famed opera house La Scala in Milan. He also is the recipient of the 2012 Louis Sudler Prize in the Arts, which recognizes outstanding artistic talent.

Aucoin’s mother is musical, his father is a writer, and there were always hundreds of books, and plenty of scores lying around the house. But his parents, he said, “never forced me into anything.”

He was smitten with music the moment he banged on the keys of his grandparents battered, out-of-tune, upright piano at age 6. Soon, a composer was born.

With composition, said Aucoin, “The thoughts aren’t always clear. It’s a kind of need. And for me, that need was awoken by Beethoven.” He recalled wandering his backyard after hearing Beethoven’s Ninth Symphony and wondering, “How could something this good have been created?”

He composed his first piece, “a twangy sort of Americana thing,” shortly after, and soon fell in love with opera’s fusion of words and song, completing his first libretto and score at age 9. Years of intense study of the piano followed, but by the time he was a teenager he suffered “a crisis of faith” in classical music. He retreated, playing the keyboard with his indie-rock band Elephantom and studying jazz. The break reinvigorated his love of the classical canon and inspired him to look beyond the conservatory to a place where he could chart his own musical path.

“It seemed I could make my own musical life [at Harvard] in a way I couldn’t anywhere else. I really loved that independent spirit,” he told the Gazette in February.

While at Harvard, Aucoin blazed his own artistic trail. He wrote and directed two operas, including “Hart Crane,” based on the troubled American poet, which premiered at the Loeb Drama Center in April. He also coached and accompanied countless Harvard singers, and served as music director for the Dunster House Opera Society and as assistant conductor for the Harvard-Radcliffe Orchestra (HRO).

“I think he is an unstoppable force of nature … beyond talented and gifted,” said HRO Director Federico Cortese. “He is a hypersensitive poet with amazing abilities and a voracious taste for music.”

A classmate and fellow musician called Aucoin “the kind of person that really makes you glad you went to Harvard.”

Aucoin said his introduction to poetry came later because “as a really young kid you are open to music in a way you are not open to nuances of language quite yet. To understand poetry, words need to have accumulated multiple shades of meaning for you.” He credits the creative energy of his peers at The Harvard Advocate and of his mentor, Boylston Professor of Rhetoric and Oratory Jorie Graham, for helping him to develop a “personal language in which you find our own rules.”

Aucoin arrived for a recent morning interview with a mop of curly wet hair, en route to observe a rehearsal at the Boston Symphony Orchestra for the remainder of the day. This fall he will work as a musical assistant at the Metropolitan Opera, study composition at the Juilliard School, and direct the new orchestra/opera company at the Peabody Essex Museum.

It’s hard to imagine Aucoin, whose face doesn’t hold even the promise of a wrinkle, leading professional musicians, many of whom have been performing longer than he has been alive. But he sees the job as inspiring confidence in players and performers regardless of their age.

“I think of it as being a lightning rod, not the hand of Zeus,” he said. “You have to be able to give an intensity back to the orchestra.”

If his Harvard career is any indication, Aucoin will have intensity to spare.

Posted in Campus & Community, Colleen Walsh, Commencement, Harvard-Radcliffe Orchestra, Jorie Graham, Juilliard School, Kirkland House, Metropolitan Opera, Office for the Arts, Peabody Essex Museum, The Harvard Advocate | Tagged , , , , , , , , , , | Comments Off

Yaz Lawsuit Breaking News

By admin | Published May 17, 2012

Yaz Lawsuit Update 05/17/2012: It has yet to be determined how many more Yaz Lawsuits Bayer will have to face. It is clear that the case is not near an end despite the fact that Bayer is already in settlement talks with a large number of plaintiffs that have already filed a Yaz Lawsuit.

The Yaz Lawsuit was filed on behalf of all plaintiffs involved as a single lawsuit although each plaintiff’s damages were set forth individually.

This Yaz Lawsuit was filed based on the following cause(s) of action: strict products liability, breach of express and implied warranty, negligence, negligence per se, fraudulent misrepresentation, fraudulent concealment, fraud, negligent misrepresentation, and unjust enrichment brought by Plaintiffs for damages associated with their ingestion of the pharmaceutical drug YAZ/Yasmin, also known generically as Drospirenone and Ethinyl Estradiol .

 

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‘Voice of public service at Harvard’

By Harvard Gazette | Published May 17, 2012

Calling the Harvard Kennedy School (HKS) “the voice of public service at Harvard,” University President Drew Faust welcomed alumni from across seven decades Friday to a special 75th anniversary conference at the Charles Hotel.

“The Kennedy School motto ‘Ask what you can do’ is a resonant theme that extends across Harvard and makes all of us so much more aware of what it means to have these responsibilities and how they might be exercised,” Faust said. “The Harvard Kennedy School is a powerful embodiment and representation to the world of a fundamental University value, and that is why facts and knowledge matter as societies and nations make choices about the future.”

Faust noted the School’s “wide range of influence,” both in terms of its esteemed graduates — from U.N. Secretary-General Ban Ki-moon, M.P.A. ’84, and Liberian President Ellen Johnson Sirleaf, M.P.A. ’71, to “50 members of Congress both past and present,” and the many “world changing” ideas and programs that have taken form at HKS over its history.

“The Kennedy School has even changed the language we speak. I think that is a fundamental indicator of influence,” Faust said.  “Phrases like ‘soft power’ have entered the lexicon and become central to the language of international affairs. ‘Bowling alone’ is a term of our national conversation about the fraying of civic ties. So the influence of the Kennedy School has been extensive and deep — internationally, nationally, and how we understand ourselves, even how we talk about our world.”

It is the dual mission of training leaders and conducting important research, Faust said, that makes the School and the University more relevant than ever.

“That is what we stand for: that knowledge and learning, evidence-based decision-making can have a huge positive impact on the world, and the Kennedy School leads the parade in advancing that conception in the circles of power and government and policy,” she said.

HKS Dean David T. Ellwood focused his opening remarks on the School’s evolution from its founding in 1936, explaining that it wasn’t until President John F. Kennedy took office that “suddenly public service and the idea of government service became cool.”

“It highlights the most important thing we can do to begin with, which is to get spectacular people of great character, great intelligence, great energy, and great desire to make a difference to come here,” he said.

HKS Dean David T. Ellwood provided an overview of some of the School's key priorities, including technology and governance, behavioral and decision sciences, and making democracy work.

Ellwood provided an overview of some of the School’s key priorities, including technology and governance, behavioral and decision sciences, and making democracy work.

Other plenary sessions focused on governing in the digital age, economic inequality, and the Middle East and North Africa.  The lunchtime keynote address, “The Future of Power,” was delivered by Joseph S. Nye, Harvard University Distinguished Service Professor and former HKS dean.

The conference, titled “HKS at 75: A Time of Peril and Promise for the World” is among the highlights of Reunion Weekend 2012.

 

Posted in 75th anniversary, Campus & Community, David T. Ellwood, Doug Gavel, Drew Faust, Harvard Kennedy School, Harvard Traditions | Tagged , , , , , , | Comments Off

Actos Lawsuit Discovery

By admin | Published May 17, 2012

acActos Lawsuit: There is a very close relationship between survival of an individual and the stage of bladder cancer at diagnosis. For superficial disease, five year survival rates are greater than 90%. Once the cancer has spread into the bladder muscle and beyond, survival is markedly reduced. Five year survival in those with T2 disease (tumor invading superficial bladder muscle) is 60-75%, T3 disease (tumor invading deep muscle) 36-58%, and for those with T4 disease (tumor invading surrounding organs) or with node positive disease, 4-35%.’ With distant (metastatic) spread, survival at five years is less than 5%.

Most individuals with bladder cancer will undergo an initial removal of their bladder tumor by biopsy or for larger tumors by resection of their tumor via a resectoscope. For complete details see Chapter 8. Once this tumor is removed, the pathologist will determine and report on the extent of tumor invasion into the wall of the bladder. If the tumor has grown into the prostate, tissue removal via the resectoscope from this location will also be reviewed and reported pathologically. This pathologic diagnosis determines the initial stage of the cancer.

When dealing with large tumors after the initial cancer resection, your urologist may do a manual exam under anesthesia. By pressing deeply on the pelvis, the urologist may be able to palpate the tumor and assess its possible spread beyond the bladder. With modern technology and the availability of the CT scan, the manual exam is now of less importance. The CT scan can often visualize a thickened or distorted bladder wall, indicating the possibility of tumor involvement or extension through the wall. More importantly, it can determine spread to adjacent organs or lymph node involvement. Distant spread into the abdomen or beyond may also be seen. Other studies, such as the Bone Scan or Chest X ray can assess the presence and extent of metastatic diseases, MRI can be used for those with limited kidney function that cannot have a CT scan. More recently, Positron Emission Tomography (PET) scan has become available. This study can sometimes locate small deposits of metastatic disease not visible on CT or MRI scan.

Our use of the term or terms Actos Lawsuit is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

Actos Lawsuit

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Paxil Lawsuit Process Notice

By admin | Published May 17, 2012

Paxil Lawsuit News – 5/14/2012: Did you take Paxil? Please contact us today if you took Paxil and later experienced harmful side effects. We will connect you with a lawyer that is experienced in complex litigation that may be able to help you recover monetary damages.

Paxil Lawsuit: Of the more than 600 lawsuits against Glaxo, this case was the first Paxil birth defect lawsuit to go to trial. According to the complaint, the child’s mother took Paxil as prescribed by her doctor during her pregnancy. The child suffered from a direct Paxil side effect. The manufacturer disagrees with the verdict and stated that they would appeal. There seem to be serious potential risks to taking Paxil while pregnant. There are many lawsuits against Paxil because of the negative side effects that are possible. If you or someone you know has a baby who was born with a birth defect because of using Paxil during pregnancy, you should contact a Paxil birth defects attorney. No child should have to suffer from a heart defect as a result of a medication taken during pregnancy. You should consult your physician and speak in detail regarding Paxil’s potential risks. You should also consider switching to a different antidepressant if these medications are absolutely necessary for you to take.

Paxil Lawsuit News: News and Information

Paxil Lawsuit: Risks of taking this drug may need to be updated and made even stronger in order to fully provide information to people who are considering taking the medication. Paxil is considered to be an antidepressant, specifically a selective serotonin reuptake inhibitors (SSRI). The drug works by restoring the balance of serotonin in the brain. Serotonin helps to improve certain mood problems. Paxil has been used to treat depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder and premenstrual dysphoric disorder. Like any other drug, there are side effects from Paxil that need to be made apparent to those who are taking the drug. Because of the side effects, there have been Paxil lawsuits.

Our use of the term or terms Paxil Lawsuit is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

To keep up to date on Paxil Lawsuit visit our site often.

Paxil Lawsuit Process

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Actos Lawsuit Enlightenment

By admin | Published May 17, 2012

Actos Lawsuit: A small amount of microscopic hematuria in an individual without symptoms (asymptomatic microscopic hematuria) can be found in many healthy individuals. It has been estimated that up to 10% of the population has asymptomatic microscopic hematuria. In brief, the older you are (generally over the age of 40), the more risk factors you have (smoking, occupational exposure), and the more red blood cells present, the more likely serious pathology (disease of the urinary tract including bladder cancer) will be found. If you have persistent microscopic hematuria without a known cause, a urologic assessment is recommended.

When assessment for hematuria is required, the entire urinary tract is evaluated. This is accomplished via imaging studies (X ray or ultrasound), cystoscopy (visual inspection of the bladder), and possibly cytology (urine test for cancer cells). There are multiple causes for blood in the urine, including the possibility of kidney disease, kidney, ureteral or bladder stones, infection, or enlargement of the prostate. Approximately twenty percent of patients with bladder cancer will complain of irritative voiding symptoms. These symptoms include urinary urgency (a need to rush to the bathroom), burning and urinary frequency. These same symptoms are present in other urologic conditions such as infection, bladder instability and prostatic enlargement in men. These symptoms are most commonly associated with a diffuse superficial form of transitional cell cancer of the bladder called CIS (carcinoma in situ). Unfortunately for some, their diagnosis may be delayed since these symptoms are present in so many other diseases.

Actos Lawsuit

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Paxil Lawsuit Reports

By admin | Published May 16, 2012

Paxil Lawsuit News – 5/11/2012: Did you take Paxil? Please contact us today if you took Paxil and later experienced harmful side effects. We will connect you with a lawyer that is experienced in complex litigation that may be able to help you recover monetary damages.

Paxil Lawsuit: Studies have suggested a link between the use of Paxil during pregnancy and birth defects. Paxil is an antidepressant that is classified as a Selective Serotonin Reuptake Inhibitor (SSRI). Among all the studies, it was concluded that women who took Paxil while pregnant increased the risk of their children developing birth defects, particularly heart defects. The side effects of Paxilare dangerous and can be potentially life-threatening so it is important to be aware of all the risks. Before the studies were conducted, the U.S. Food and Drug Administration (FDA) issued a Paxil warning to doctors, other healthcare professionals and patients. The FDA Paxil warning alerted the public about the increased risk of congenital malformations, particularly heart malformations, as a result of using Paxil during the first trimester of pregnancy. In 2006, after the FDA warning for Paxil users, the American College of Obstetricians and Gynecologists (ACOG) warned pregnant women to avoid taking the prescription medication Paxil. ACOG officials specifically noted the detrimental side effects of Paxilregarding heart defects for newborns.

Some of the latest studies, performed in association with the CDC, make note of the Paxil side effects and suggest an increased risk of neonatal heart defects for the infants of obese women who were pregnant and used Paxil. Another study that was published in The New England Journal of Medicine also suggested that heart defects were a side effect of Paxil. These Paxil birth defects obstruct the blood flow from the heart to the lungs. Heart defects are not the only side effects associated with Paxil. Another Paxil birth defect includes a lung condition called Persistent Pulmonary Hypertension (PPHN). Babies born with PPHN have difficulty getting enough oxygen to their lungs and may possibly suffer from heart failure. The side effects of Paxil are potentially dangerous and life-threatening and should be considered by mothers who are pregnant before beginning the use of the antidepressant Paxil. If your baby was born with a medical condition as a result of being exposed to Paxil, you should contact a Paxil birth defects lawyer for a consultation.

Our use of the term or terms Paxil Lawsuit is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

To keep up to date on Paxil Lawsuit visit our site often.

Paxil Lawsuit

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Actos Lawsuit Headlines

By admin | Published May 16, 2012

Actos Lawsuit: T2 lesions: tumors in this stage have superficially invaded the muscularis propria, the thick muscle layer of the bladder. These tumors usually are high grade. Although they may be amenable to local therapy, they have a high rate of further invasion and are at high risk for developing metastatic disease. T3 lesions: these tumors are almost always high grade, nodular, and very aggressive. Unfortunately, many may actually be under­staged tumors with the cancer already spread beyond the confines of the bladder. When an individual develops muscle invasive bladder cancer, major intervention is required to prevent spread and save the life of the individual. T4 lesions: high grade invasive, aggressive tumors which have invaded adjacent organs. Many of these have also spread to distant parts of the body (are understaged) and are incurable.

A number of other factors may be utilized to help predict the likelihood of recurrence and progression of an individual’s bladder cancer after treatment. Tumor size: There generally is little difference in the recurrence rates of small tumors (tumors approximately 1-3 cm in size or V2-I Vi inches in size). As tumors grow to mid size and larger, it is generally believed that recurrence rates are increased. Tumor Configuration: More important than the size alone is the actual appearance of the tumor. Tumors that are papillary in appearance usually have a better prognosis than tumors that are solid (sessile or nodular). Multifocality: When multiple tumors are present, scattered over various sites, the prognosis is worsened. If CIS is present in conjunction with bladder tumors, the rate of recurrence and progression is markedly worsened. Having multiple sites affected represents a widespread abnormal urothelium with an increased risk of future disease.

Our use of the term or terms Actos Lawsuit is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

Actos Lawsuit

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